AKUSZTIKUS ÉLVEZET:A zene ,ami örömhormont termel.

urbi ÉLJ BOLDOGAN! Vas, 2011-01-16 23:45

Anatomically distinct dopamine release during anticipation
and experience of peak emotion to music

Valorie N Salimpoor, Mitchel Benovoy, Kevin Larcher, Alain Dagher & Robert J Zatorre

Nature Neuroscience (2011) doi:10.1038/nn.2726

Received 07 October 2010 Accepted 25 November 2010 Published online 09 January 2011

Music, an abstract stimulus, can arouse feelings of euphoria and craving, similar to tangible rewards that involve the striatal dopaminergic system.

Using the neurochemical specificity of [11C]raclopride positron emission tomography scanning, combined with psychophysiological measures of autonomic nervous system activity, we found endogenous dopamine release in the striatum at peak emotional arousal during music listening.

To examine the time course of dopamine release, we used functional magnetic resonance imaging with the same stimuli and listeners, and found a functional dissociation: the caudate was more involved during the anticipation and the nucleus accumbens was more involved during the experience of peak emotional responses to music.

These results indicate that intense pleasure in response to music can lead to dopamine release in the striatal system. Notably, the anticipation of an abstract reward can result in dopamine release in an anatomical pathway distinct from that associated with the peak pleasure itself.

Our results help to explain why music is of such high value across all human societies.